Joe was a 60-year-old man — fit, active, and seemingly well. He’d seen his doctor multiple times over several months with non-specific symptoms.
When Bea met Joe in the emergency department as a junior doctor, all that had changed. He was jaundiced and had lost significant weight. A scan confirmed he had metastatic pancreatic cancer.
In the conversation that followed, Joe never asked: Why do I have cancer?”
What he asked was:
That question changed everything. Joe’s story wasn’t an anomaly – it was the same story as thousands of others.
A story of a system not built to detect
cancer early enough.
Unfortunately, like many, Joe didn’t make it.
That question - and the people behind it - became our why.
Dr Bea Bakshi and Dr Miles Payling founded C the Signs with one mission: to make early cancer detection the norm — not the exception.
Because no one’s life should depend on chance, timing, or a system that waits too long to act. We’re making sure cancer is found earlier - so every patient gets the care they need, when it matters most.
As clinicians, we set out to give every patient the same care we’d want for those we love. But the tools we had weren’t built to find cancer early - so we built one that was.
As NHS doctors, we know what it’s like when someone slips through the net - but we’ve also seen what’s possible when they’re caught in time. The joy. The relief. Getting back to living life.
That’s why we’ve built a new way to find cancer early - using real-time data, evidence-based pathways, and AI to make early detection accessible to everyone. Because early detection isn’t just possible - it’s essential. And patients aren’t statistics. They’re parents, colleagues, neighbours. They’re us.
We’re proud to have started in the NHS — shaped by the values it was built on: care, equity, and access for all. Now we’re taking our vision global - so wherever you live, early detection becomes possible and survival the norm.
C the Signs is more than AI — it’s a movement to make early cancer detection possible for everyone, no matter who they are or where they’re from.
Cancer is the second leading cause of death worldwide. It doesn’t discriminate — but access to diagnosis too often does. A person’s chance of survival should never depend on where they live, what they earn, the colour of their skin, their gender, or their ability to pay.
Early diagnosis and access to care should be a basic human right. Early detection is the single biggest predictor of survival. And every patient deserves that chance.
This is where our movement begins — with patients, clinicians, policymakers, researchers, and innovators. Together, we can redefine what’s possible, and rewrite the future of cancer.
C the Signs brings together clinicians, engineers, data scientists, researchers, and patient advocates - united by one goal: to change the way the world finds cancer. We reflect the diversity of the systems and communities we serve, and we’re working together to write a new story for health - one built on early action, equity, and life-saving care.
Behind C the Signs is a group of world-class advisors - clinicians, scientists, technologists, researchers, and health leaders - guiding our work with deep expertise and lived experience.
Their insight helps shape our vision, challenge our thinking, and ensure we stay focused on what matters most: improving outcomes, driving equity, and transforming early cancer detection around the world.